San Francisco’s healthtech scene sits at the intersection of software, healthcare delivery, diagnostics, AI, and consumer platforms. It is a market where founders are not just building apps for wellness or care access, but reworking how chronic disease is managed, how clinicians document care, how hospitals move faster, how mental health practices operate, and how patients access their own data.
For a city that has already produced major fintech, crypto, AI, and enterprise software companies, healthtech is a natural next lane: ambitious, capital-intensive, deeply regulated, and increasingly central to how technology reshapes everyday life.
Andrew Dudum
Co-founder & CEO — Hims & Hers
Andrew Dudum leads one of the Bay Area’s most visible consumer health companies. Hims & Hers has grown from a telehealth-focused brand into a scaled public company spanning multiple care categories, and its latest results underscore how large that platform has become. The company reported approximately $2.35 billion in 2025 revenue, more than 2.5 million subscribers, and continued growth heading into 2026, making Dudum a clear founder to watch for anyone following the next phase of direct-to-consumer healthcare.
Daniel Perez
Co-founder & CEO — Hinge Health
Daniel Perez has built Hinge Health into one of the Bay Area’s most important digital care companies, focused on musculoskeletal treatment and employer-sponsored care. Hinge identifies Perez as its co-founder and chief executive officer, and the company has continued to frame its opportunity around software-driven, AI-powered care delivery at scale. That puts Perez in a strong position within San Francisco healthtech: he is not just operating in telehealth, but in the larger movement to automate parts of care delivery while expanding access through employer and health-plan channels.
Sean Duffy
Co-founder & CEO — Omada Health
Sean Duffy has been a longstanding name in Bay Area digital health, and Omada Health remains one of the clearest examples of a company tackling chronic disease through a software-enabled model. Omada identifies Duffy as co-founder and CEO, and its recent updates show continued momentum around member-facing AI and GLP-1 companion support as the chronic-care market evolves. That combination of category durability and product expansion makes Duffy one of the strongest healthtech founder profiles in the region.
Chris Mansi
CEO & Co-founder — Viz.ai
Chris Mansi represents a different side of San Francisco healthtech: AI built for clinical workflows and acute care coordination. Viz.ai identifies Mansi as CEO and co-founder, and the company entered 2026 highlighting record scale, broader health-system adoption, and profitability in its healthcare business. For a founder list, that makes Mansi especially notable because his company sits at the junction of healthcare AI, hospital operations, and real-world clinical impact.
Lucia Huang
Co-founder & CEO — Osmind
Lucia Huang brings mental health infrastructure into the feature, which broadens the list beyond primary care and hospital software. Osmind identifies Huang as CEO and co-founder and positions the company around supporting psychiatry practices and advancing evidence generation for moderate to severe mental health conditions. More recent company updates also show Osmind leaning into the operational needs of modern psychiatric care, especially as practices work with treatments such as Spravato, TMS, and ketamine.
Noga Leviner
Co-founder & CEO — PicnicHealth
Noga Leviner’s work at PicnicHealth adds the patient-record and real-world research angle to San Francisco healthtech. PicnicHealth identifies Leviner as co-founder and CEO, and the company says its direct-to-patient model and technology platform have enabled 12 of the top 20 largest life sciences companies to run more efficient observational or non-interventional research. That positions Leviner as a founder worth watching not just for patient experience, but for the broader question of how data infrastructure, AI, and research operations are converging in healthcare.
Andrew Lacy
Founder & CEO — Prenuvo
Andrew Lacy has helped push preventative imaging into a much more visible category within Bay Area healthtech. Prenuvo identifies Lacy as founder and CEO and is based in Redwood City, with continued expansion and product development around whole-body MRI and AI-powered preventive health tools. Lacy is a strong inclusion because Prenuvo sits at the intersection of diagnostics, consumer health, premium care experiences, and the broader shift toward earlier detection rather than reactive treatment.
Tanay Tandon
Co-founder & CEO — Commure
Tanay Tandon rounds out the list with one of the Bay Area’s most infrastructure-oriented healthcare software stories. Commure identifies Tandon as co-founder and chief executive officer, and the company says its platform supports more than 40 million ambient appointments, over $25 billion in annual claims, and more than 150 health systems. In 2025, it also announced $200 million in growth financing. That scale, combined with its focus on revenue cycle, ambient AI, and enterprise health-system workflows, makes Tandon one of the clearest founders to watch for readers interested in where healthcare software is heading next.
Why HealthTech Remains a Key San Francisco Industry
San Francisco remains one of the few places where consumer technology instincts, enterprise software discipline, AI talent, and healthcare ambition all coexist at scale. The founders on this list reflect that mix. Some are building consumer-facing care brands, others are reengineering hospital workflows, mental health operations, diagnostics, or research infrastructure.
Together, they show why healthtech remains one of the most important adjacent industries to watch after fintech, crypto, AI, and enterprise software. It is still producing companies with large market ambition, strong Bay Area roots, and the potential to reshape how healthcare is delivered and experienced.
The Bay Area’s healthcare innovation story also runs through the infrastructure layer. Read the San Francisco Bay Area Cloud Infrastructure Founders to Watch in 2026 for another look at the founders building the systems that power modern software and services.
